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Publication list:

Sánchez-Huertas C, Bonhomme M, Falco A, Fagotto-Kaufmann C, van Haren J, Jeanneteau F, Galjart N, Debant A, Boudeau J. The +TIP Navigator-1 is an actin–microtubule crosslinker that regulates axonal growth cone motility.J Cell Biol (2020) 219 (9): e201905199. doi: 10.1083/jcb.201905199.
Journal of Cell Biology, Article


Wittmann T*, Dema A, van Haren J*. Lights, cytoskeleton, action: Optogenetic control of cell dynamics. Current Opinion in Cell Biology. 2020; doi: 10.1016/j.ceb.2020.03.003, *Corresponding Author
Current Opinion in Cell Biology, Review


van Haren J, Adachi LS, Wittmann T. Optogenetic Control of Microtubule Dynamics. Methods Mol Biol. 2020;2101:211-234. doi: 10.1007/978-1-0716-0219-5_14. PubMed PMID: 31879907.
Methods in Molecular Biology, Book Chapter


van Haren J*, Wittmann T*. Microtubule Plus End Dynamics - Do We Know How Microtubules Grow?: Cells boost microtubule growth by promoting distinct structural transitions at growing microtubule ends. Bioessays. 2019 Mar;41(3):e1800194. doi: 10.1002/bies.201800194. Epub 2019 Feb 7. PubMed PMID: 30730055. *Corresponding Author
BioEssays, Review

van Haren J, Charafeddine RA, Ettinger A, Wang H, Hahn KM, Wittmann T. Local control of intracellular microtubule dynamics by EB1 photodissociation. Nature Cell Biology, 2018 Mar 20; (3):252-261. doi: 10.1038/s41556-017-0028-5. Epub 2018 Jan 29.
Nature Cell Biology, Article

Wittmann T, van Haren J. Generation of cell lines with light-controlled microtubule dynamics. Protocol Exchange, 2018, published online 29 January 2018. doi:10.1038/protex.2017.155
Protocol Exchange, Protocols

Pemble H, Kumar P, van Haren J, Wittmann T. GSK3-mediated CLASP2 phosphorylation modulates kinetochore dynamics. Journal of Cell Science, 2017 Apr 15; 130(8):1404-1412. doi: 10.1242/jcs.194662. Epub 2017 Feb 23.
Journal of Cell Science, Article

Ettinger A, van Haren J, Ribeiro SA, Wittmann T. Doublecortin Is Excluded from Growing Microtubule Ends and Recognizes the GDP-Microtubule Lattice. Current Biology, 2016 Jun 20; 26(12):1549-1555. doi: 10.1016/j.cub.2016.04.020. Epub 2016 May 26.
Current Biology, Article


van Haren J, Boudeau J, Schmidt S, Basu S, Liu Z, Lammers D, Demmers J, Benhari J, Grosveld F, Debant A, Galjart N. Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension. Current Biology, 2014 Aug 4; 24(15):1778-85. doi: 10.1016/j.cub.2014.06.037. Epub 2014 Jul 24.
Current Biology, Article

Ruiz-Saenz A, van Haren J, Sayas CL, Rangel L, Demmers J, Millán J, Alonso MA, Galjart N, Correas I. Protein 4.1R binds to CLASP2 and regulates dynamics, organization and attachment of microtubules to the cell cortex. Journal of Cell Science, 2013 Oct 15; 126(Pt 20):4589-601. doi: 10.1242/jcs.120840. Epub 2013 Aug 13.
Journal of Cell Science, Article

Ghamari A, van de Corput MP, Thongjuea S, van Cappellen WA, van Ijcken W, van Haren J, Soler E, Eick D, Lenhard B, Grosveld FG. In vivo live imaging of RNA polymerase II transcription factories in primary cells. Genes and Development, 2013 Apr 1; 27(7):767-77. doi: 10.1101/gad.216200.113.
Genes and Development, Article

Drabek K, Gutiérrez L, Vermeij M, Clapes T, Patel SR, Boisset JC, van Haren J, Pereira AL, Liu Z, Akinci U, Nikolic T, van Ijcken W, van den Hout M, Meinders M, Melo C, Sambade C, Drabek D, Hendriks RW, Philipsen S, Mommaas M, Grosveld F, Maiato H, Italiano JE Jr, Robin C, Galjart N. The microtubule plus-end tracking protein CLASP2 is required for hematopoiesis and hematopoietic stem cell maintenance. Cell Reports. 2012 Oct 25; 2(4): 781-8. doi: 10.1016/j.celrep.2012.08.040. Epub 2012 Oct 19.
Cell Reports, Article

Schmidt N, Basu S, Sladecek S, Gatti S, van Haren J, Treves S, Pielage J, Galjart N, Brenner HR. Agrin regulates CLASP2-mediated capture of microtubules at the neuromuscular junction synaptic membrane. Journal of Cell Biology. 2012 Aug 6; 198(3): 421-37. doi: 10.1083/jcb.201111130. Epub 2012 Jul 30.
Journal of Cell Biology, Article

Lee HS, Komarova YA, Nadezhdina ES, Anjum R, Peloquin JG, Schober JM, Danciu O, van Haren J, Galjart N, Gygi SP, Akhmanova A, Borisy GG. Phosphorylation controls autoinhibition of cytoplasmic linker protein-170. Molecular Biology of the Cell, 2010 Aug 1; 21(15):2661-73. doi: 10.1091/mbc.E09-12-1036. Epub 2010 Jun 2.
Molecular Biology of the Cell, Article

Stepanova T, Smal I, van Haren J, Akinci U, Liu Z, Miedema M, Limpens R, van Ham M, van der Reijden M, Poot R, Grosveld F, Mommaas M, Meijering E, Galjart N. History-dependent catastrophes regulate axonal microtubule behavior. Current Biology, 2010 Jun 8; 20(11):1023-8. doi: 10.1016/j.cub.2010.04.024. Epub 2010 May 13.
Current Biology, Article

van Haren J, Draegestein K, Keijzer N, Abrahams JP, Grosveld F, Peeters PJ, Moechars D, Galjart N. Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions. Cell Motilily and the Cytoskeleton, 2009 Oct; 66(10):824-38. doi: 10.1002/cm.20370.
Cell Motility and the Cytoskeleton, Article

Dragestein KA, van Cappellen WA, van Haren J, Tsibidis GD, Akhmanova A, Knoch TA, Grosveld F, Galjart N. Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends.
Journal of Cell Biology, Article

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